Heather Fottler Mangian
Senior Research Specialist

FSHN
Bevier Hall 420
905 S. Goodwin Ave.
Urbana, IL 61801
Office: 217.244.6952
Lab: 217.265.0776
E-mail: mangian@uiuc.edu

Education/Training

  • B.A., Biological Sciences, Monmouth College, Monmouth, IL.
  • M.S., Animal Sciences, Nutrition, University of Illinois at Urbana-Champaign.
  • Teaching Certification: Secondary Science, Biology, Chemistry; grades 9-12.

Professional Experience

  • Senior Research Specialist, Food Science and Human Nutrition, University of Illinois at Urbana-Champaign, 1996 to present (except 2000-2003).
  • Biology Teacher, Champaign Unit 4, Centennial High School, Champaign, 2000-2003.
  • Senior Research Specialist in Health Sciences, College of Medicine, University of Illinois at Urbana-Champaign, 1979 to 1996.
  • Research Assistant, Department of Animal Sciences, College of Agriculture, University of Illinois, Urbana Campus, 1977 to 1979.

Publications

  1. Mangian, H. F., Deutsch, A. S. & Tappenden, K. A. (2006) Butyrate activates the GLUT2 promoter and induces gene transcription in enterocyte-like Caco2-BBe cells. Faseb Journal 20: A547-A547.
  2. Tappenden, K. A., Albin, D. M., Bartholome, A. L. & Mangian, H. F. (2003) Glucagon-like peptide-2 and short-chain fatty acids: A new twist to an old story. Journal of Nutrition 133: 3717-3720.
  3. Rains, T. M., Mangian, H. F., Liang, T., Cole, A. C., Beverly, J. L. & Shay, N. F. (2001) Growth hormone-releasing factor affects macronutrient intake during the anabolic phase of zinc repletion: Total hypothalamic growth hormone-releasing factor content and growth hormone-releasing factor immunoneutralization during zinc repletion. Nutritional Neuroscience 4: 283-293.
  4. Shay, N. F. & Mangian, H. F. (2000) Neurobiology of zinc-influenced eating behavior. Journal of Nutrition 130: 1493s-1499s.
  5. Shay, N. F., Ezzatkhah, M., Prisecaru, V. I. & Mangian, H. F. (1999) Zinc deficiency does not affect self-selection of dietary protein in 2-choice macronutrient preference tests using albumin or purified amino acids. Faseb Journal 13: A215-A215.
  6. Mangian, H. F., Williamson, S. & Shay, N. F. (1999) Hypothalamic neuropeptide expression during the initiation of zinc deficiency. Faseb Journal 13: A570-A570.
  7. Mukherjee, P., Sotnikov, A. V., Mangian, H. J., Zhou, J. R., Visek, W. J. & Clinton, S. K. (1999) Energy intake and prostate tumor growth, angiogenesis, and vascular endothelial growth factor expression. Journal of the National Cancer Institute 91: 512-523.
  8. Mukherjee, P., Zhou, J., Sotnikov, A., Mangian, H., Blackburn, G., Visek, W. & Clinton, S. (1998) Energy intake stimulates prostate tumor growth by enhancing VEGF expression and tumor angiogenesis. Faseb Journal 12: A658-A658.
  9. Rains, T. M., Mangian, H. F., Cole, A. C., Liang, T., Beverly, J. L. & Shay, N. F. (1998) Growth hormone releasing factor content in discrete hypothalamic sites and immunoneutralization of GRF during recovery from zinc deficiency. Faseb Journal 12: A235-A235.
  10. Mangian, H. F., Lee, R. G., Paul, G. L., Emmert, J. L. & Shay, N. F. (1998) Zinc deficiency suppresses plasma leptin concentrations in rats. Journal of Nutritional Biochemistry 9: 47-51.
  11. Park, E. I., Paisley, E. A., Mangian, H. J., Swartz, D. A., Wu, M. X., OMorchoe, P. J., Behr, S. R., Visek, W. J. & Kaput, J. (1997) Lipid level and type alter stearoyl CoA desaturase mRNA abundance differently in mice with distinct susceptibilities to diet-influenced diseases. Journal of Nutrition 127: 566-573.
  12. Mangian, H. F., Li, G., Paul, G. L. & Shay, N. F. (1997) Blood leptin levels are reduced during zinc deficiency-induced anorexia. Faseb Journal 11: 1124-1124.
  13. Clinton, S. K., Mulloy, A. L., Li, S. P., Mangian, H. J. & Visek, W. J. (1997) Dietary fat and protein intake differ in modulation of prostate tumor growth, prolactin secretion and metabolism, and prostate gland prolactin binding capacity in rats. Journal of Nutrition 127: 225-237.
  14. Paisley, E. A., Park, E. I., Swartz, D. A., Mangian, H. J., Visek, W. J. & Kaput, J. (1996) Temporal-regulation of serum lipids and stearoyl CoA desaturase and lipoprotein lipase mRNA in BALB/cHnn mice. Journal of Nutrition 126: 2730-2737.
  15. Paisley, E. A., Mangian, H. J., Visek, W. J. & Kaput, J. (1996) Serum lipids and hepatic Apo E gene expression in female BALB/c mice in response to fasting and feeding. Faseb Journal 10: 2784-2784.
  16. Mangian, H. J., Paisley, E. A., Park, E., Wu, M., Swartz, D. A., Romanczyk, L., Mcclelland, C., Behr, S., Visek, W. J. & Kaput, J. (1995) Gene-Expression and Serum-Lipid Profiles in Inbred Mice Fed Different Levels and Types of Fat. Faseb Journal 9: A177-A177.
  17. Kaput, J., Swartz, D., Paisley, E., Mangian, H., Daniel, W. L. & Visek, W. J. (1994) Diet-Disease Interactions at the Molecular-Level - an Experimental Paradigm. Journal of Nutrition 124: S1296-S1305.
  18. Mangian, H. J., Paisley, E. A., Visek, W. J. & Kaput, J. (1994) Differential Display of Mammary-Gland Genes in Mice Fed Different Levels of Fat. Faseb Journal 8: A887-A887.
  19. Paisley, E. A., Mangian, H. J., Visek, W. J. & Kaput, J. (1994) Characterization of Diet Regulated Genes Following Differential Display. Faseb Journal 8: A887-A887.
  20. Garwood, W. E., Chu, C. T. W., Visek, W. J. & Mangian, H. J. (1994) Relationship of in-Vitro Properties of Medium Pore Zeolite Zsm-5 to in-Vivo Performance. Abstracts of Papers of the American Chemical Society 207: 326-INOR.
  21. Paisley, E. A., Mangian, H. J., Visek, W. J. & Kaput, J. (1993) Characterization of Diet Regulated Genes Isolated from Cdna Libraries. Faseb Journal 7: A166-A166.
  22. Mangian, H. J., Paisley, E. A., Kaput, J. & Visek, W. J. (1993) Transcriptional and Rflp Analysis of a Diet Regulated Gene. Faseb Journal 7: A166-A166.
  23. Elliott, T. S., Swartz, D. A., Paisley, E. A., Mangian, H. J., Visek, W. J. & Kaput, J. (1993) F1fo-Atpase Subunit-E Gene Isolated in a Screen for Diet Regulated Genes. Biochemical and Biophysical Research Communications 190: 167-174.
  24. Visek, W. J., Prior, R. L., Ulman, E. A. & Mangian, H. (1992) Additive Depression of Liver Arginase by Dietary Deficiencies of Arginine and Manganese. Faseb Journal 6: A1951-A1951.
  25. Clinton, S. K., Imrey, P. B., Mangian, H. J., Nandkumar, S. & Visek, W. J. (1992) The Combined Effects of Dietary-Fat, Protein, and Energy-Intake on Azoxymethane-Induced Intestinal and Renal Carcinogenesis. Cancer Research 52: 857-865.
  26. Clinton, S. K., Bostwick, D. G., Olson, L. M., Mangian, H. J. & Visek, W. J. (1988) Effects of Ammonium Acetate and Sodium Cholate on N-Methyl-N'-Nitro-N-Nitrosoguanidine-Induced Colon Carcinogenesis of Rats. Cancer Research 48: 3035-3039.
  27. Clinton, S. K., Nandkumar, S., Mangian, H. J. & Visek, W. J. (1988) The Inhibition of Azoxymethane-Induced Colon Carcinogenesis by Castration in Male-Rats. Faseb Journal 2: A1155-A1155.
  28. Visek, W. J., Mangian, H., Elliott, T. S., Ruskin, B., Bragg, D. S. A. & Robinson, J. L. (1988) Renal Damage and Urinary Lithiasis in Mice Fed Orotic-Acid (Oa). Faseb Journal 2: A863-A863.
  29. Clinton, S. K., Bostwick, D. G., Mangian, H. J. & Visek, W. J. (1986) Ammonia and Cholic-Acid as Promoters of N-Methyl-N'-Nitrosoguanidine (Mnng) Induced Colon Carcinogenesis in Rats. Proceedings of the American Association for Cancer Research 27: 131-131.
  30. Anderson, P. A., Alster, J. M., Clinton, S. K., Imrey, P. B., Mangian, H. J., Truex, C. R. & Visek, W. J. (1985) Plasma Amino-Acids and Excretion of Protein End Products by Mice Fed 10-Percent or 40-Percent Soybean Protein Diets with or without Dietary Benzo[a]Pyrene or 1,2-Dimethylhydrazine. Journal of Nutrition 115: 1515-1527.
  31. Hevia, P., Truex, C. R., Imrey, P. B., Clinton, S. K., Mangian, H. J. & Visek, W. J. (1984) Plasma Amino-Acids and Excretion of Protein End Products by Mice Fed 10-Percent or 40-Percent Soybean Protein Diets with or without Dietary 2-Acetylaminofluorene or N,N-Dinitrosopiperazine. Journal of Nutrition 114: 555-564.
  32. Visek, W. J., Mangian, H. J. & Shoemaker, J. D. (1984) Correlation of Urinary Orotic-Acid (Oa) with Liver Lipid-Content in Rats Fed Ethanol. Federation Proceedings 43: 495-495.
  33. Olsowka, E. S., Mangian, H. J. & Visek, W. J. (1983) Dietary Arginine (Arg) and Fat Interactions on Orotic Aciduria and Plasma Amino-Acids in Growing-Rats. Federation Proceedings 42: 542-542.
  34. Fahey Jr., G.C., M.L. Moore, H.J. Fottler, and J.E. Corbin. 1983. Digestibility and metabolism tests for evaluation of ingredient contributions to dog foods. Pet Food Ind. Day Proc., p48.
  35. Brown, D.E., H.J. Fottler, J.L. Pugh, G.C. Fahey Jr., and J.E. Corbin. 1983. Effects of elfazepam on feed intake, feeding behavior, and nutrient utilization by the dog. Pet Food Ind. Day Proc. p77.
  36. Brown, D.E., H.J. Fottler, J.L. Pugh, G.C. Fahey Jr., and J.E. Corbin. 1981. Effects of elfazepam on feed intake, feeding behavior and nutrient utilization by the dog. Nutr. Reports Int'l 53: 1538-1544.
  37. Moore, M.L., H.J. Fottler, G.C. Fahey, Jr. and J.E. Corbin. 1980. Utilization of Corn-Soybean Meal-Substituted Diets by Dogs. J. An. Sci. 50:5, 892-896.
  38. Fottler, H.J., J.L. Pugh, D.E. Brown, G.C. Fahey Jr., and J. E. Corbin. 1979. Effect of elfazepam on behavior food intake and nutrient metabolism in the dog. J. An. Sci. 48(suppl. 1): 242.
  39. Moore, M. L., H.J. Fottler, J.E. Corbin, and G.C. Fahey Jr. 1978. Utilization of corn - soy substituted diets by dogs. J. An. Sci.47(suppl.1):12.